MCCC Biomanufacturing Course / 1.13 Downstream Processing eLearning Modules html package
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Keywords
Biomanufacturing, Biotechnology, Upstream Processing, Processing, Equipment, Media, Preparation, Cells, Culture, Fermentation, Growth, Banking, Bioreactors, Primary, Recovery, Harvest, Scale-up, Single-use, Centrifugation, Downstream Processing, Quality Control, Media Preparation, Clarification, Filtration, Chromatography, Viral clearance, Inactivation, Validation, Qualification, Column, Bed, Maintenance, Ultrafiltration, Diafiltration, Bioburden, TFF, Tangential flow filtration, Bulk Fill
Project
c3bc
Authors
O'Neill, Jack
Wallman, Sonia
Bryans, Margaret
Date Submitted
2016-03-30
Material Type
Hybrid/Blended Course
Secondary Material Type
Institution
Montgomery College
Industry Partner
Novartis GlaxoSmithKline
License
CC BY
Funding Source
TAACCCT Round 2
Additional Public Access
Abstract
"This learning object,1.13 Downstream Processing eLearning Modules html package, is an introduction to biopharmaceutical production and provides an overview of the biomanufacture of a monoclonal drug within a virtualized downstream processing environment. This educational tool utilizes text, illustrations, and video animations (e-learning) to detail the workflow, operations, and instrumentation involved in the batch production of a monoclonal antibody under cGMP conditions.
This object details a typical downstream production workflow for a monoclonal antibody and includes activities such as: bioreactor operations, harvest and clarification, multiple membrane filtration steps, a series of chromatography purifications, Ultrafiltration/Diafiltration, and bulk fill. Support materials include resources such as: text, illustrations, animations, interactive activities, and self-assessments. Once a participant has completed a review of the modules, self-assessments provide a means to check your knowledge.
This e-learning material was developed in part referencing the Introduction to Biomanufacturing textbook, Northeast Biomanufacturing Center and Collaborative, Published 2012. The platform is packaged as a zip file. After the files are unzipped (extracted), the learning object can be accessed and viewed with a web-browser (Google Chrome, Firefox, and Windows Explorer). It is associated with a READ ME (instructions) file on how to install and run the application, READ ME Simple Instructions to Access the DSP html.
This learning object is associated with additional learning content in biomanufacturing that is provided as separate, supplemental material:
a) The eleven lectures intended for use for instructing a biomanufacturing course, MCCC Biomanufacturing Course / 1.1 Introduction to Biomanufacturing to 1.11 Process Development.
b) The MCCC Biomanufacturing Course / 1.12 Montgomery County Community College Biomanufacturing Laboratory Manual 2nd Edition. This manual covers a variety of experiments relevant to biomanufacturing, is SOP driven, and includes batch record documentation.
c) The MCCC Biomanufacturing Course / 1.14 Downstream Processing eLearning LMS SCORM package. This educational tool utilizes text, figures, and video animations to detail the workflow, operations, and instrumentation involved in the batch production of a monoclonal antibody under cGMP conditions. This SCORM is packaged as a zip file and is best accessed and viewed with a Learning Management System, LMS
This grant product was created by the Community College Consortium for Bioscience Credentials and is licensed under a Creative Commons Attribution."
Industry (NAISC)
Professional, Scientific, and Technical Services -- Professional, Scientific, and Technical Services (541)
Occupation (SOC)
Life, Physical, and Social Science Occupations -- Biological Technicians (19-4021)
Instructional Program (CIP)
Biological and Biomedical Sciences (26)
Credit Type
Credential Type
None
Educational Level
1st year Community College or equivalent